Does PERTUZUMAB Cause Hypertransaminasaemia? 57 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 57 reports of Hypertransaminasaemia have been filed in association with PERTUZUMAB (PERJETA). This represents 0.3% of all adverse event reports for PERTUZUMAB.
57
Reports of Hypertransaminasaemia with PERTUZUMAB
0.3%
of all PERTUZUMAB reports
0
Deaths
15
Hospitalizations
How Dangerous Is Hypertransaminasaemia From PERTUZUMAB?
Of the 57 reports, 15 (26.3%) required hospitalization, and 10 (17.5%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 57 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which PERTUZUMAB Alternatives Have Lower Hypertransaminasaemia Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN