Does PHENYTOIN Cause Acute hepatic failure? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Acute hepatic failure have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.3% of all adverse event reports for PHENYTOIN.
41
Reports of Acute hepatic failure with PHENYTOIN
0.3%
of all PHENYTOIN reports
11
Deaths
36
Hospitalizations
How Dangerous Is Acute hepatic failure From PHENYTOIN?
Of the 41 reports, 11 (26.8%) resulted in death, 36 (87.8%) required hospitalization, and 7 (17.1%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
Yes, Acute hepatic failure is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PHENYTOIN Alternatives Have Lower Acute hepatic failure Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS