Does PONATINIB Cause Acute hepatic failure? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Acute hepatic failure have been filed in association with PONATINIB (Iclusig). This represents 0.1% of all adverse event reports for PONATINIB.
9
Reports of Acute hepatic failure with PONATINIB
0.1%
of all PONATINIB reports
8
Deaths
3
Hospitalizations
How Dangerous Is Acute hepatic failure From PONATINIB?
Of the 9 reports, 8 (88.9%) resulted in death, 3 (33.3%) required hospitalization, and 2 (22.2%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PONATINIB. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PONATINIB Alternatives Have Lower Acute hepatic failure Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE