Does PONATINIB Cause Necrosis? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Necrosis have been filed in association with PONATINIB (Iclusig). This represents 0.1% of all adverse event reports for PONATINIB.
6
Reports of Necrosis with PONATINIB
0.1%
of all PONATINIB reports
0
Deaths
6
Hospitalizations
How Dangerous Is Necrosis From PONATINIB?
Of the 6 reports, 6 (100.0%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PONATINIB. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which PONATINIB Alternatives Have Lower Necrosis Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE