Does PROCARBAZINE Cause Splenomegaly? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Splenomegaly have been filed in association with PROCARBAZINE (Matulane). This represents 0.5% of all adverse event reports for PROCARBAZINE.
33
Reports of Splenomegaly with PROCARBAZINE
0.5%
of all PROCARBAZINE reports
1
Deaths
32
Hospitalizations
How Dangerous Is Splenomegaly From PROCARBAZINE?
Of the 33 reports, 1 (3.0%) resulted in death, 32 (97.0%) required hospitalization, and 32 (97.0%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROCARBAZINE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does PROCARBAZINE Cause?
Nausea (1,029)
Fatigue (890)
Vomiting (375)
Neutropenia (311)
Off label use (301)
Constipation (274)
Platelet count decreased (246)
White blood cell count decreased (229)
Headache (222)
Acute myeloid leukaemia (195)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which PROCARBAZINE Alternatives Have Lower Splenomegaly Risk?
PROCARBAZINE vs PROCHLORPERAZINE
PROCARBAZINE vs PROCHLORPERAZINE EDISYLATE
PROCARBAZINE vs PROCRIT
PROCARBAZINE vs PROCYCLIDINE
PROCARBAZINE vs PROGESTERONE