Does PROPYLTHIOURACIL Cause Hepatic failure? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hepatic failure have been filed in association with PROPYLTHIOURACIL (Propylthiouracil). This represents 1.5% of all adverse event reports for PROPYLTHIOURACIL.
14
Reports of Hepatic failure with PROPYLTHIOURACIL
1.5%
of all PROPYLTHIOURACIL reports
2
Deaths
11
Hospitalizations
How Dangerous Is Hepatic failure From PROPYLTHIOURACIL?
Of the 14 reports, 2 (14.3%) resulted in death, 11 (78.6%) required hospitalization, and 2 (14.3%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROPYLTHIOURACIL. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does PROPYLTHIOURACIL Cause?
Drug ineffective (121)
Foetal exposure during pregnancy (110)
Anti-neutrophil cytoplasmic antibody positive vasculitis (81)
Exposure during pregnancy (75)
Hyperthyroidism (58)
Off label use (54)
Maternal exposure during pregnancy (50)
Agranulocytosis (42)
Vasculitis (41)
Premature baby (38)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PROPYLTHIOURACIL Alternatives Have Lower Hepatic failure Risk?
PROPYLTHIOURACIL vs PROTAMINE
PROPYLTHIOURACIL vs PROTHIPENDYL
PROPYLTHIOURACIL vs PROTIONAMIDE
PROPYLTHIOURACIL vs PROTONIX
PROPYLTHIOURACIL vs PROTOPIC