Does PYRAZINAMIDE Cause Clostridium difficile colitis? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Clostridium difficile colitis have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 0.7% of all adverse event reports for PYRAZINAMIDE.
36
Reports of Clostridium difficile colitis with PYRAZINAMIDE
0.7%
of all PYRAZINAMIDE reports
17
Deaths
33
Hospitalizations
How Dangerous Is Clostridium difficile colitis From PYRAZINAMIDE?
Of the 36 reports, 17 (47.2%) resulted in death, 33 (91.7%) required hospitalization, and 12 (33.3%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which PYRAZINAMIDE Alternatives Have Lower Clostridium difficile colitis Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB