Does PYRAZINAMIDE Cause Hepatitis? 123 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 123 reports of Hepatitis have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 2.2% of all adverse event reports for PYRAZINAMIDE.
123
Reports of Hepatitis with PYRAZINAMIDE
2.2%
of all PYRAZINAMIDE reports
14
Deaths
60
Hospitalizations
How Dangerous Is Hepatitis From PYRAZINAMIDE?
Of the 123 reports, 14 (11.4%) resulted in death, 60 (48.8%) required hospitalization, and 10 (8.1%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 123 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which PYRAZINAMIDE Alternatives Have Lower Hepatitis Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB