Does PYRAZINAMIDE Cause Hypothyroidism? 38 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Hypothyroidism have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 0.7% of all adverse event reports for PYRAZINAMIDE.
38
Reports of Hypothyroidism with PYRAZINAMIDE
0.7%
of all PYRAZINAMIDE reports
12
Deaths
25
Hospitalizations
How Dangerous Is Hypothyroidism From PYRAZINAMIDE?
Of the 38 reports, 12 (31.6%) resulted in death, 25 (65.8%) required hospitalization, and 1 (2.6%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 38 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which PYRAZINAMIDE Alternatives Have Lower Hypothyroidism Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB