Does REGORAFENIB Cause Acute hepatic failure? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Acute hepatic failure have been filed in association with REGORAFENIB (Stivarga). This represents 0.2% of all adverse event reports for REGORAFENIB.
22
Reports of Acute hepatic failure with REGORAFENIB
0.2%
of all REGORAFENIB reports
15
Deaths
12
Hospitalizations
How Dangerous Is Acute hepatic failure From REGORAFENIB?
Of the 22 reports, 15 (68.2%) resulted in death, 12 (54.5%) required hospitalization, and 9 (40.9%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for REGORAFENIB. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does REGORAFENIB Cause?
Off label use (1,906)
Fatigue (1,530)
Palmar-plantar erythrodysaesthesia syndrome (1,230)
Diarrhoea (1,221)
Decreased appetite (941)
Asthenia (825)
Death (813)
Dysphonia (702)
Nausea (688)
Pain in extremity (686)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which REGORAFENIB Alternatives Have Lower Acute hepatic failure Risk?
REGORAFENIB vs REGORAFENIB\REGORAFENIB
REGORAFENIB vs RELATLIMAB
REGORAFENIB vs RELPAX
REGORAFENIB vs RELUGOLIX
REGORAFENIB vs REMDESIVIR