Does REGORAFENIB Cause Large intestine perforation? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Large intestine perforation have been filed in association with REGORAFENIB (Stivarga). This represents 0.2% of all adverse event reports for REGORAFENIB.
17
Reports of Large intestine perforation with REGORAFENIB
0.2%
of all REGORAFENIB reports
3
Deaths
13
Hospitalizations
How Dangerous Is Large intestine perforation From REGORAFENIB?
Of the 17 reports, 3 (17.6%) resulted in death, 13 (76.5%) required hospitalization, and 4 (23.5%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for REGORAFENIB. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does REGORAFENIB Cause?
Off label use (1,906)
Fatigue (1,530)
Palmar-plantar erythrodysaesthesia syndrome (1,230)
Diarrhoea (1,221)
Decreased appetite (941)
Asthenia (825)
Death (813)
Dysphonia (702)
Nausea (688)
Pain in extremity (686)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which REGORAFENIB Alternatives Have Lower Large intestine perforation Risk?
REGORAFENIB vs REGORAFENIB\REGORAFENIB
REGORAFENIB vs RELATLIMAB
REGORAFENIB vs RELPAX
REGORAFENIB vs RELUGOLIX
REGORAFENIB vs REMDESIVIR