Does RIFAMPIN Cause Splenomegaly? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Splenomegaly have been filed in association with RIFAMPIN (Rifampin). This represents 0.2% of all adverse event reports for RIFAMPIN.
31
Reports of Splenomegaly with RIFAMPIN
0.2%
of all RIFAMPIN reports
15
Deaths
24
Hospitalizations
How Dangerous Is Splenomegaly From RIFAMPIN?
Of the 31 reports, 15 (48.4%) resulted in death, 24 (77.4%) required hospitalization, and 12 (38.7%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIFAMPIN. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does RIFAMPIN Cause?
Drug ineffective (1,238)
Drug reaction with eosinophilia and systemic symptoms (1,049)
Drug interaction (735)
Pyrexia (735)
Acute kidney injury (684)
Drug-induced liver injury (684)
Off label use (640)
Condition aggravated (597)
Nausea (572)
Paradoxical drug reaction (570)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which RIFAMPIN Alternatives Have Lower Splenomegaly Risk?
RIFAMPIN vs RIFAMYCIN
RIFAMPIN vs RIFAPENTINE
RIFAMPIN vs RIFAXIMIN
RIFAMPIN vs RILMENIDINE
RIFAMPIN vs RILONACEPT