Does ROMIPLOSTIM Cause Splenomegaly? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Splenomegaly have been filed in association with ROMIPLOSTIM (Nplate). This represents 0.3% of all adverse event reports for ROMIPLOSTIM.
23
Reports of Splenomegaly with ROMIPLOSTIM
0.3%
of all ROMIPLOSTIM reports
5
Deaths
12
Hospitalizations
How Dangerous Is Splenomegaly From ROMIPLOSTIM?
Of the 23 reports, 5 (21.7%) resulted in death, 12 (52.2%) required hospitalization, and 2 (8.7%) were considered life-threatening.
Is Splenomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ROMIPLOSTIM. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does ROMIPLOSTIM Cause?
Off label use (1,027)
Platelet count decreased (892)
Platelet count abnormal (703)
Drug ineffective (513)
Thrombocytopenia (369)
Headache (359)
Death (356)
Product storage error (344)
Fatigue (251)
Circumstance or information capable of leading to medication error (238)
What Other Drugs Cause Splenomegaly?
RUXOLITINIB (1,995)
RITUXIMAB (326)
PREDNISONE (299)
IBRUTINIB (279)
CYCLOPHOSPHAMIDE (254)
METHOTREXATE (253)
OXALIPLATIN (253)
ADALIMUMAB (245)
TACROLIMUS (218)
IMATINIB (216)
Which ROMIPLOSTIM Alternatives Have Lower Splenomegaly Risk?
ROMIPLOSTIM vs ROMOSOZUMAB
ROMIPLOSTIM vs ROMOSOZUMAB-AQQG
ROMIPLOSTIM vs ROPEGINTERFERON ALFA-2B-NJFT
ROMIPLOSTIM vs ROPINIROLE
ROMIPLOSTIM vs ROPIVACAINE