Does SIMEPREVIR Cause Acute hepatic failure? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Acute hepatic failure have been filed in association with SIMEPREVIR. This represents 0.3% of all adverse event reports for SIMEPREVIR.
19
Reports of Acute hepatic failure with SIMEPREVIR
0.3%
of all SIMEPREVIR reports
11
Deaths
16
Hospitalizations
How Dangerous Is Acute hepatic failure From SIMEPREVIR?
Of the 19 reports, 11 (57.9%) resulted in death, 16 (84.2%) required hospitalization, and 5 (26.3%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMEPREVIR. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does SIMEPREVIR Cause?
Off label use (1,166)
Anaemia (999)
Platelet count decreased (833)
White blood cell count decreased (581)
Hepatitis c (537)
Blood bilirubin increased (467)
Drug ineffective (440)
Pyrexia (429)
Rash (388)
Haemoglobin decreased (385)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which SIMEPREVIR Alternatives Have Lower Acute hepatic failure Risk?
SIMEPREVIR vs SIMPONI
SIMEPREVIR vs SIMVASTATIN
SIMEPREVIR vs SINGULAIR
SIMEPREVIR vs SINTILIMAB
SIMEPREVIR vs SIPONIMOD