Does SIMVASTATIN Cause Large intestine perforation? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Large intestine perforation have been filed in association with SIMVASTATIN (Simvastatin). This represents 0.1% of all adverse event reports for SIMVASTATIN.
18
Reports of Large intestine perforation with SIMVASTATIN
0.1%
of all SIMVASTATIN reports
15
Deaths
6
Hospitalizations
How Dangerous Is Large intestine perforation From SIMVASTATIN?
Of the 18 reports, 15 (83.3%) resulted in death, 6 (33.3%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMVASTATIN. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does SIMVASTATIN Cause?
Myalgia (3,919)
Fatigue (2,066)
Arthralgia (1,775)
Drug interaction (1,744)
Nausea (1,676)
Rhabdomyolysis (1,616)
Dyspnoea (1,542)
Headache (1,470)
Drug hypersensitivity (1,433)
Muscular weakness (1,356)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which SIMVASTATIN Alternatives Have Lower Large intestine perforation Risk?
SIMVASTATIN vs SINGULAIR
SIMVASTATIN vs SINTILIMAB
SIMVASTATIN vs SIPONIMOD
SIMVASTATIN vs SIPULEUCEL-T
SIMVASTATIN vs SIROLIMUS