Does SIMVASTATIN Cause Necrosis? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Necrosis have been filed in association with SIMVASTATIN (Simvastatin). This represents 0.1% of all adverse event reports for SIMVASTATIN.
19
Reports of Necrosis with SIMVASTATIN
0.1%
of all SIMVASTATIN reports
2
Deaths
8
Hospitalizations
How Dangerous Is Necrosis From SIMVASTATIN?
Of the 19 reports, 2 (10.5%) resulted in death, 8 (42.1%) required hospitalization, and 7 (36.8%) were considered life-threatening.
Is Necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMVASTATIN. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does SIMVASTATIN Cause?
Myalgia (3,919)
Fatigue (2,066)
Arthralgia (1,775)
Drug interaction (1,744)
Nausea (1,676)
Rhabdomyolysis (1,616)
Dyspnoea (1,542)
Headache (1,470)
Drug hypersensitivity (1,433)
Muscular weakness (1,356)
What Other Drugs Cause Necrosis?
METHOTREXATE (155)
PREDNISONE (143)
TACROLIMUS (120)
ADALIMUMAB (119)
MYCOPHENOLATE MOFETIL (101)
CYCLOPHOSPHAMIDE (97)
RITUXIMAB (97)
GLATIRAMER (84)
PREDNISOLONE (83)
METHYLPREDNISOLONE (76)
Which SIMVASTATIN Alternatives Have Lower Necrosis Risk?
SIMVASTATIN vs SINGULAIR
SIMVASTATIN vs SINTILIMAB
SIMVASTATIN vs SIPONIMOD
SIMVASTATIN vs SIPULEUCEL-T
SIMVASTATIN vs SIROLIMUS