Does SIROLIMUS Cause Acute hepatic failure? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Acute hepatic failure have been filed in association with SIROLIMUS (sirolimus). This represents 0.1% of all adverse event reports for SIROLIMUS.
13
Reports of Acute hepatic failure with SIROLIMUS
0.1%
of all SIROLIMUS reports
12
Deaths
7
Hospitalizations
How Dangerous Is Acute hepatic failure From SIROLIMUS?
Of the 13 reports, 12 (92.3%) resulted in death, 7 (53.8%) required hospitalization.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIROLIMUS. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which SIROLIMUS Alternatives Have Lower Acute hepatic failure Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE