Does SORAFENIB Cause Large intestine perforation? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Large intestine perforation have been filed in association with SORAFENIB (sorafenib). This represents 0.2% of all adverse event reports for SORAFENIB.
16
Reports of Large intestine perforation with SORAFENIB
0.2%
of all SORAFENIB reports
6
Deaths
10
Hospitalizations
How Dangerous Is Large intestine perforation From SORAFENIB?
Of the 16 reports, 6 (37.5%) resulted in death, 10 (62.5%) required hospitalization, and 2 (12.5%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SORAFENIB. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which SORAFENIB Alternatives Have Lower Large intestine perforation Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK