Does SOTORASIB Cause Hepatic failure? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Hepatic failure have been filed in association with SOTORASIB (LUMAKRAS). This represents 0.4% of all adverse event reports for SOTORASIB.
11
Reports of Hepatic failure with SOTORASIB
0.4%
of all SOTORASIB reports
1
Deaths
5
Hospitalizations
How Dangerous Is Hepatic failure From SOTORASIB?
Of the 11 reports, 1 (9.1%) resulted in death, 5 (45.5%) required hospitalization.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOTORASIB. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does SOTORASIB Cause?
Non-small cell lung cancer (483)
Death (319)
Disease progression (314)
Diarrhoea (284)
Off label use (193)
Nausea (98)
Non-small cell lung cancer metastatic (93)
Hepatotoxicity (91)
Fatigue (87)
Hepatic function abnormal (80)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which SOTORASIB Alternatives Have Lower Hepatic failure Risk?
SOTORASIB vs SOTROVIMAB
SOTORASIB vs SOVALDI
SOTORASIB vs SOYBEAN OIL
SOTORASIB vs SPARSENTAN
SOTORASIB vs SPARTALIZUMAB