Does TACROLIMUS Cause Hyperbilirubinaemia? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Hyperbilirubinaemia have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.1% of all adverse event reports for TACROLIMUS.
121
Reports of Hyperbilirubinaemia with TACROLIMUS
0.1%
of all TACROLIMUS reports
36
Deaths
63
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From TACROLIMUS?
Of the 121 reports, 36 (29.8%) resulted in death, 63 (52.1%) required hospitalization, and 14 (11.6%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TACROLIMUS. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which TACROLIMUS Alternatives Have Lower Hyperbilirubinaemia Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB