Does TACROLIMUS Cause Large intestine perforation? 125 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 125 reports of Large intestine perforation have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.1% of all adverse event reports for TACROLIMUS.
125
Reports of Large intestine perforation with TACROLIMUS
0.1%
of all TACROLIMUS reports
35
Deaths
87
Hospitalizations
How Dangerous Is Large intestine perforation From TACROLIMUS?
Of the 125 reports, 35 (28.0%) resulted in death, 87 (69.6%) required hospitalization, and 38 (30.4%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TACROLIMUS. However, 125 reports have been filed with the FAERS database.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which TACROLIMUS Alternatives Have Lower Large intestine perforation Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB