Does THALIDOMIDE Cause Large intestine perforation? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Large intestine perforation have been filed in association with THALIDOMIDE (Thalomid). This represents 0.1% of all adverse event reports for THALIDOMIDE.
21
Reports of Large intestine perforation with THALIDOMIDE
0.1%
of all THALIDOMIDE reports
2
Deaths
11
Hospitalizations
How Dangerous Is Large intestine perforation From THALIDOMIDE?
Of the 21 reports, 2 (9.5%) resulted in death, 11 (52.4%) required hospitalization, and 1 (4.8%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THALIDOMIDE. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does THALIDOMIDE Cause?
Plasma cell myeloma (1,652)
Off label use (1,356)
Death (1,161)
Neuropathy peripheral (1,068)
Drug ineffective (789)
Pneumonia (694)
Fatigue (643)
Constipation (461)
Thrombocytopenia (429)
Neutropenia (420)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which THALIDOMIDE Alternatives Have Lower Large intestine perforation Risk?
THALIDOMIDE vs THALOMID
THALIDOMIDE vs THEOPHYLLINE
THALIDOMIDE vs THEOPHYLLINE ANHYDROUS
THALIDOMIDE vs THIAMINE
THALIDOMIDE vs THIOCOLCHICOSIDE