TOPIRAMATE for Depression: Side Effects & Safety Data
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There are 163 adverse event reports in the FDA FAERS database where TOPIRAMATE was used for Depression.
Most Reported Side Effects for TOPIRAMATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 5,553 | 19.4% | 642 | 1,391 |
| Off label use | 4,248 | 14.9% | 932 | 1,409 |
| Product use in unapproved indication | 2,173 | 7.6% | 579 | 752 |
| Headache | 1,997 | 7.0% | 416 | 697 |
| Drug intolerance | 1,820 | 6.4% | 533 | 549 |
| Migraine | 1,796 | 6.3% | 371 | 558 |
| Nausea | 1,691 | 5.9% | 420 | 597 |
| Seizure | 1,535 | 5.4% | 44 | 447 |
| Paraesthesia | 1,506 | 5.3% | 431 | 538 |
| Dizziness | 1,466 | 5.1% | 414 | 534 |
| Fatigue | 1,423 | 5.0% | 423 | 606 |
| Product use issue | 1,345 | 4.7% | 366 | 425 |
| Pain | 1,254 | 4.4% | 578 | 637 |
| Vomiting | 1,212 | 4.2% | 515 | 676 |
| Depression | 1,182 | 4.1% | 456 | 551 |
Other Indications for TOPIRAMATE
Product used for unknown indication (8,128)
Migraine (5,515)
Epilepsy (2,828)
Seizure (1,931)
Migraine prophylaxis (1,227)
Headache (709)
Partial seizures (534)
Status epilepticus (454)
Generalised tonic-clonic seizure (361)
Weight decreased (251)
Other Drugs Used for Depression
SERTRALINE (14,497)
VENLAFAXINE (11,868)
DULOXETINE (11,681)
ESKETAMINE (10,058)
ESCITALOPRAM OXALATE (7,373)
FLUOXETINE (7,035)
BUPROPION (6,165)
MIRTAZAPINE (6,021)
CITALOPRAM HYDROBROMIDE (5,450)
PAROXETINE (5,386)