Does TOPIRAMATE Cause Exostosis? 66 Reports in FDA Database

Q: Does TOPIRAMATE cause Exostosis?

66 reports of Exostosis have been filed with the FDA for TOPIRAMATE, representing 0.2% of all TOPIRAMATE adverse event reports.

Q: How dangerous is Exostosis from TOPIRAMATE?

Of 66 reports, 63 (95.5%) resulted in death and 64 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Exostosis have been filed in association with TOPIRAMATE (Topiramate). This represents 0.2% of all adverse event reports for TOPIRAMATE.

Reports of Exostosis with TOPIRAMATE

0.2%

of all TOPIRAMATE reports

Deaths

Hospitalizations

How Dangerous Is Exostosis From TOPIRAMATE?

Of the 66 reports, 63 (95.5%) resulted in death, 64 (97.0%) required hospitalization, and 63 (95.5%) were considered life-threatening.

Is Exostosis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 66 reports have been filed with the FAERS database.

What Other Side Effects Does TOPIRAMATE Cause?

Drug ineffective (5,553) Off label use (4,248) Product use in unapproved indication (2,173) Headache (1,997) Drug intolerance (1,820) Migraine (1,796) Nausea (1,691) Seizure (1,535) Paraesthesia (1,506) Dizziness (1,466)

What Other Drugs Cause Exostosis?

ADALIMUMAB (2,008) METHOTREXATE (968) ETANERCEPT (918) ABATACEPT (775) TOCILIZUMAB (768) LEFLUNOMIDE (743) SULFASALAZINE (712) DICLOFENAC (702) TOFACITINIB (702) CERTOLIZUMAB PEGOL (695)

Which TOPIRAMATE Alternatives Have Lower Exostosis Risk?

TOPIRAMATE vs TOPOTECAN TOPIRAMATE vs TOPOTECAN\TOPOTECAN TOPIRAMATE vs TOPROL TOPIRAMATE vs TOREMIFENE TOPIRAMATE vs TORIPALIMAB

TOPIRAMATE Full Profile All Exostosis Reports All Drugs Causing Exostosis TOPIRAMATE Demographics