Does TRABECTEDIN Cause Hepatic cytolysis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Hepatic cytolysis have been filed in association with TRABECTEDIN (YONDELIS). This represents 0.9% of all adverse event reports for TRABECTEDIN.
18
Reports of Hepatic cytolysis with TRABECTEDIN
0.9%
of all TRABECTEDIN reports
3
Deaths
14
Hospitalizations
How Dangerous Is Hepatic cytolysis From TRABECTEDIN?
Of the 18 reports, 3 (16.7%) resulted in death, 14 (77.8%) required hospitalization, and 5 (27.8%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRABECTEDIN. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does TRABECTEDIN Cause?
Neutropenia (207)
Anaemia (189)
Thrombocytopenia (172)
Nausea (160)
Febrile neutropenia (142)
Pancytopenia (124)
Vomiting (121)
Rhabdomyolysis (117)
Off label use (105)
Alanine aminotransferase increased (104)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which TRABECTEDIN Alternatives Have Lower Hepatic cytolysis Risk?
TRABECTEDIN vs TRACLEER
TRABECTEDIN vs TRADJENTA
TRABECTEDIN vs TRALOKINUMAB-LDRM
TRABECTEDIN vs TRAMADOL
TRABECTEDIN vs TRAMADOL\TRAMADOL