Does TRASTUZUMAB Cause Hypertransaminasaemia? 114 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 114 reports of Hypertransaminasaemia have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.2% of all adverse event reports for TRASTUZUMAB.
114
Reports of Hypertransaminasaemia with TRASTUZUMAB
0.2%
of all TRASTUZUMAB reports
8
Deaths
18
Hospitalizations
How Dangerous Is Hypertransaminasaemia From TRASTUZUMAB?
Of the 114 reports, 8 (7.0%) resulted in death, 18 (15.8%) required hospitalization, and 13 (11.4%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 114 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which TRASTUZUMAB Alternatives Have Lower Hypertransaminasaemia Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE