Does TRASTUZUMAB Cause Large intestine perforation? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Large intestine perforation have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.1% of all adverse event reports for TRASTUZUMAB.
35
Reports of Large intestine perforation with TRASTUZUMAB
0.1%
of all TRASTUZUMAB reports
14
Deaths
24
Hospitalizations
How Dangerous Is Large intestine perforation From TRASTUZUMAB?
Of the 35 reports, 14 (40.0%) resulted in death, 24 (68.6%) required hospitalization, and 8 (22.9%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which TRASTUZUMAB Alternatives Have Lower Large intestine perforation Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE