Does VALPROATE Cause Acute hepatic failure? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Acute hepatic failure have been filed in association with VALPROATE (Valproate Sodium). This represents 0.3% of all adverse event reports for VALPROATE.
51
Reports of Acute hepatic failure with VALPROATE
0.3%
of all VALPROATE reports
22
Deaths
36
Hospitalizations
How Dangerous Is Acute hepatic failure From VALPROATE?
Of the 51 reports, 22 (43.1%) resulted in death, 36 (70.6%) required hospitalization, and 10 (19.6%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROATE. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which VALPROATE Alternatives Have Lower Acute hepatic failure Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE