Does VALPROATE Cause Large intestine perforation? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Large intestine perforation have been filed in association with VALPROATE (Valproate Sodium). This represents 0.1% of all adverse event reports for VALPROATE.
12
Reports of Large intestine perforation with VALPROATE
0.1%
of all VALPROATE reports
2
Deaths
3
Hospitalizations
How Dangerous Is Large intestine perforation From VALPROATE?
Of the 12 reports, 2 (16.7%) resulted in death, 3 (25.0%) required hospitalization, and 11 (91.7%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROATE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which VALPROATE Alternatives Have Lower Large intestine perforation Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE