Does VALPROIC ACID Cause Hepatic cytolysis? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Hepatic cytolysis have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.1% of all adverse event reports for VALPROIC ACID.
28
Reports of Hepatic cytolysis with VALPROIC ACID
0.1%
of all VALPROIC ACID reports
4
Deaths
19
Hospitalizations
How Dangerous Is Hepatic cytolysis From VALPROIC ACID?
Of the 28 reports, 4 (14.3%) resulted in death, 19 (67.9%) required hospitalization, and 7 (25.0%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which VALPROIC ACID Alternatives Have Lower Hepatic cytolysis Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN