Does VEMURAFENIB Cause Hyperbilirubinaemia? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Hyperbilirubinaemia have been filed in association with VEMURAFENIB (ZELBORAF). This represents 0.2% of all adverse event reports for VEMURAFENIB.
20
Reports of Hyperbilirubinaemia with VEMURAFENIB
0.2%
of all VEMURAFENIB reports
1
Deaths
4
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From VEMURAFENIB?
Of the 20 reports, 1 (5.0%) resulted in death, 4 (20.0%) required hospitalization, and 2 (10.0%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VEMURAFENIB. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does VEMURAFENIB Cause?
Rash (1,202)
Arthralgia (783)
Off label use (782)
Fatigue (773)
Diarrhoea (655)
Nausea (601)
Pyrexia (569)
Death (505)
Alopecia (445)
Decreased appetite (383)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which VEMURAFENIB Alternatives Have Lower Hyperbilirubinaemia Risk?
VEMURAFENIB vs VENETOCLAX
VEMURAFENIB vs VENLAFAXINE
VEMURAFENIB vs VENTAVIS
VEMURAFENIB vs VENTOLIN
VEMURAFENIB vs VENTOLIN HFA