Anti-epileptic Agent [EPC]: Side Effects & Safety Data for 14 Drugs
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Anti-epileptic Agent [EPC] includes 14 drugs with a combined 142,546 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
14
Drugs in Class
142,546
Combined Reports
All Anti-epileptic Agent [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| LAMOTRIGINE | Lamotrigine ER | 48,114 | 6,604 | 17,639 | 13.7% |
| VALPROIC ACID | Valproic Acid | 20,030 | 2,667 | 8,183 | 13.3% |
| VALPROATE | Valproate Sodium | 15,880 | 1,000 | 6,625 | 6.3% |
| PHENYTOIN | PHENYTOIN SODIUM | 14,469 | 1,449 | 5,241 | 10.0% |
| VIGABATRIN | Vigabatrin | 12,059 | 1,091 | 3,607 | 9.0% |
| DIVALPROEX | Divalproex Sodium | 11,461 | 478 | 4,169 | 4.2% |
| OXCARBAZEPINE | OXCARBAZEPINE | 10,809 | 864 | 3,159 | 8.0% |
| ZONISAMIDE | Zonisamide | 4,764 | 299 | 1,424 | 6.3% |
| PRIMIDONE | Primidone | 1,519 | 241 | 387 | 15.9% |
| FOSPHENYTOIN | CEREBYX | 1,378 | 166 | 646 | 12.0% |
| ETHOSUXIMIDE | ETHOSUXIMIDE | 1,249 | 10 | 260 | 0.8% |
| FELBAMATE | Felbamate | 473 | 28 | 145 | 5.9% |
| TIAGABINE | TIAGABINE HYDROCHLORIDE | 244 | 10 | 71 | 4.1% |
| METHSUXIMIDE | Methsuximide | 97 | 2 | 24 | 2.1% |
Common Side Effects in Anti-epileptic Agent [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 18,614 | 1,192 |
| Seizure | 13,643 | 502 |
| Off label use | 8,191 | 1,277 |
| Toxicity to various agents | 7,704 | 2,758 |
| Foetal exposure during pregnancy | 7,192 | 454 |
| Somnolence | 5,736 | 184 |
| Drug interaction | 5,578 | 399 |
| Rash | 5,089 | 751 |
| Epilepsy | 4,656 | 692 |
| Dizziness | 4,490 | 563 |