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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Somnolence: Which Medications Cause It? (142,339 Reports Across 2,112 Drugs)

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Somnolence has been reported as an adverse event with 2,112 different drugs in the FDA's FAERS database, with 142,339 total reports. 5,846 of these reports resulted in death.The drugs most commonly associated with Somnolence are PREGABALIN, QUETIAPINE, and ACETAMINOPHEN.

142,339
Total Reports
2,112
Drugs Involved
5,846
Deaths
36,048
Hospitalizations
52.5 yrs
Average Patient Age
62.0% / 38.0%
Female / Male

Which Drugs Cause Somnolence Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
PREGABALIN 5,528 5.4% 384 1,582 240
QUETIAPINE 4,394 6.0% 224 2,072 612
ACETAMINOPHEN 3,923 2.9% 537 1,898 475
GABAPENTIN 3,798 5.1% 328 1,075 278
SODIUM OXYBATE 3,642 6.0% 13 378 2
CETIRIZINE 3,058 6.4% 11 177 36
OLANZAPINE 2,612 5.1% 130 1,334 265
DIAZEPAM 2,547 6.7% 151 1,267 208
RISPERIDONE 2,496 3.2% 129 1,005 135
OXYCODONE 2,494 1.3% 310 838 118
ALPRAZOLAM 2,461 5.1% 71 1,261 250
VALBENAZINE 2,339 10.1% 7 78 3
TRAMADOL 2,331 3.1% 313 1,115 198
CLONAZEPAM 2,260 5.7% 104 824 189
LORAZEPAM 2,114 6.3% 118 1,360 168
DULOXETINE 2,105 4.0% 42 703 62
MORPHINE 2,087 1.7% 296 936 200
LEVETIRACETAM 2,070 3.3% 77 770 75
ADALIMUMAB 2,059 0.4% 166 464 29
ARIPIPRAZOLE 2,055 3.1% 46 852 150

View all 2,112 drugs →

Top 3 Drugs Associated With Somnolence

5,528 reports
4,394 reports
3,923 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)