Complement Inhibitor [EPC]: Side Effects & Safety Data for 5 Drugs
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Complement Inhibitor [EPC] includes 5 drugs with a combined 46,320 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
5
Drugs in Class
46,320
Combined Reports
All Complement Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| ECULIZUMAB | SOLIRIS | 44,190 | 4,626 | 12,421 | 10.5% |
| PEGCETACOPLAN | Empaveli | 1,369 | 84 | 252 | 6.1% |
| ZILUCOPLAN | ZILBRYSQ | 441 | 23 | 163 | 5.2% |
| AVACINCAPTAD PEGOL | IZERVAY | 202 | 3 | 2 | 1.5% |
| RAVULIZUMAB | Ultomiris | 118 | 11 | 89 | 9.3% |
Common Side Effects in Complement Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Fatigue | 5,029 | 93 |
| Off label use | 4,364 | 589 |
| Haemoglobin decreased | 3,134 | 128 |
| Headache | 2,778 | 59 |
| Death | 2,279 | 2,276 |
| Pyrexia | 2,002 | 134 |
| Dyspnoea | 1,867 | 102 |
| Drug ineffective | 1,792 | 176 |
| Asthenia | 1,773 | 97 |
| Nausea | 1,627 | 49 |