Cytochrome P450 1A2 Inhibitors [MoA]: Side Effects & Safety Data for 12 Drugs
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Cytochrome P450 1A2 Inhibitors [MoA] includes 12 drugs with a combined 116,455 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
12
Drugs in Class
116,455
Combined Reports
All Cytochrome P450 1A2 Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| CIPROFLOXACIN | Ciprofloxacin | 43,789 | 2,671 | 13,894 | 6.1% |
| AMIODARONE | Amiodarone Hydrochloride | 25,143 | 3,845 | 13,711 | 15.3% |
| CANNABIDIOL | Epidiolex | 18,243 | 1,563 | 5,149 | 8.6% |
| DEFERASIROX | Deferasirox | 11,322 | 2,661 | 4,008 | 23.5% |
| VEMURAFENIB | ZELBORAF | 8,562 | 1,040 | 2,368 | 12.1% |
| PACRITINIB | Vonjo | 2,563 | 292 | 455 | 11.4% |
| CAPMATINIB | TABRECTA | 2,301 | 583 | 388 | 25.3% |
| OSILODROSTAT | Isturisa | 1,626 | 191 | 526 | 11.7% |
| RITLECITINIB | Litfulo | 1,441 | 1 | 47 | 0.1% |
| VILOXAZINE | QELBREE | 853 | 9 | 59 | 1.1% |
| LENIOLISIB | Joenja | 570 | 6 | 54 | 1.1% |
| TRICLABENDAZOLE | EGATEN | 42 | 0 | 4 | N/A |
Common Side Effects in Cytochrome P450 1A2 Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Fatigue | 7,213 | 484 |
| Drug ineffective | 6,982 | 862 |
| Off label use | 6,863 | 1,102 |
| Diarrhoea | 6,706 | 410 |
| Drug hypersensitivity | 5,882 | 175 |
| Nausea | 5,880 | 547 |
| Seizure | 5,628 | 126 |
| Dyspnoea | 5,354 | 701 |
| Arthralgia | 5,085 | 71 |
| Death | 4,716 | 4,691 |