Cytochrome P450 1A2 Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Fatigue | 7,213 | 11 | 484 | 1,928 | 490 |
| Drug ineffective | 6,982 | 10 | 862 | 2,833 | 956 |
| Off label use | 6,863 | 11 | 1,102 | 2,839 | 617 |
| Diarrhoea | 6,706 | 11 | 410 | 2,176 | 344 |
| Drug hypersensitivity | 5,882 | 7 | 175 | 570 | 188 |
| Nausea | 5,880 | 11 | 547 | 2,217 | 385 |
| Seizure | 5,628 | 8 | 126 | 1,960 | 123 |
| Dyspnoea | 5,354 | 10 | 701 | 2,540 | 726 |
| Arthralgia | 5,085 | 11 | 71 | 1,110 | 143 |
| Death | 4,716 | 8 | 4,691 | 630 | 154 |
| Vomiting | 4,531 | 11 | 509 | 1,894 | 404 |
| Asthenia | 4,303 | 10 | 544 | 1,801 | 463 |
| Pain | 4,210 | 10 | 153 | 1,356 | 205 |
| Rash | 4,186 | 11 | 178 | 1,158 | 187 |
| Dizziness | 3,850 | 11 | 156 | 1,260 | 228 |
| Headache | 3,599 | 11 | 138 | 1,090 | 165 |
| Pyrexia | 3,392 | 11 | 384 | 2,087 | 304 |
| Drug interaction | 3,374 | 11 | 298 | 1,825 | 444 |
| Malaise | 3,369 | 11 | 262 | 1,383 | 220 |
| Product use in unapproved indication | 3,336 | 8 | 451 | 1,001 | 258 |
| Pneumonia | 3,297 | 9 | 693 | 1,898 | 274 |
| Pain in extremity | 3,152 | 9 | 59 | 797 | 112 |
| Anxiety | 2,874 | 10 | 77 | 766 | 172 |
| Weight decreased | 2,799 | 11 | 210 | 1,161 | 190 |
| Neuropathy peripheral | 2,796 | 6 | 29 | 476 | 96 |
| Condition aggravated | 2,785 | 10 | 562 | 1,385 | 448 |
| Myalgia | 2,779 | 9 | 37 | 643 | 111 |
| Acute kidney injury | 2,589 | 8 | 325 | 1,890 | 460 |
| Abdominal pain | 2,520 | 10 | 389 | 1,231 | 249 |
| Decreased appetite | 2,453 | 10 | 195 | 931 | 111 |