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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cytochrome P450 2B6 Inducers [MoA]: Side Effects & Safety Data for 15 Drugs

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Cytochrome P450 2B6 Inducers [MoA] includes 15 drugs with a combined 164,374 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

15
Drugs in Class
164,374
Combined Reports

All Cytochrome P450 2B6 Inducers [MoA] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
CARBAMAZEPINE Carbamazepine 24,577 2,156 9,608 8.8%
NILOTINIB nilotinib 23,171 4,543 4,846 19.6%
RELUGOLIX Orgovyx 20,660 958 1,699 4.6%
DABRAFENIB Tafinlar 19,305 4,165 5,325 21.6%
CANNABIDIOL Epidiolex 18,243 1,563 5,149 8.6%
PHENYTOIN PHENYTOIN SODIUM 14,469 1,449 5,241 10.0%
RITONAVIR Norvir 11,980 1,190 2,925 9.9%
EFAVIRENZ Efavirenz, Emtricitabine and Tenofovir Disoproxil Fumarate 7,893 962 1,528 12.2%
NEVIRAPINE Nevirapine 6,651 1,101 979 16.6%
CENOBAMATE Xcopri 5,643 125 1,012 2.2%
LORLATINIB Lorbrena 5,508 1,542 1,232 28.0%
SPARSENTAN FILSPARI 3,280 18 209 0.5%
FOSPHENYTOIN CEREBYX 1,378 166 646 12.0%
LEMBOREXANT DAYVIGO 989 44 278 4.4%
MITAPIVAT PYRUKYND 627 4 58 0.6%

Common Side Effects in Cytochrome P450 2B6 Inducers [MoA] Drugs

Side EffectReportsDeaths
Fatigue 11,690 546
Seizure 11,259 336
Death 10,274 10,243
Drug ineffective 9,398 646
Pyrexia 7,109 838
Hot flush 7,029 28
Off label use 6,116 723
Diarrhoea 6,017 488
Nausea 5,597 413
Dizziness 5,231 309
View detailed side effects for this class → Compare drugs in this class →