Cytochrome P450 2B6 Inhibitors [MoA]: Side Effects & Safety Data for 7 Drugs
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Cytochrome P450 2B6 Inhibitors [MoA] includes 7 drugs with a combined 36,008 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
7
Drugs in Class
36,008
Combined Reports
All Cytochrome P450 2B6 Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| CANNABIDIOL | Epidiolex | 18,243 | 1,563 | 5,149 | 8.6% |
| CRIZOTINIB | Xalkori | 9,948 | 3,173 | 2,520 | 31.9% |
| CENOBAMATE | Xcopri | 5,643 | 125 | 1,012 | 2.2% |
| PEXIDARTINIB | Turalio | 970 | 17 | 91 | 1.8% |
| VILOXAZINE | QELBREE | 853 | 9 | 59 | 1.1% |
| LEVOKETOCONAZOLE | Recorlev | 309 | 8 | 99 | 2.6% |
| TRICLABENDAZOLE | EGATEN | 42 | 0 | 4 | N/A |
Common Side Effects in Cytochrome P450 2B6 Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Seizure | 6,632 | 109 |
| Death | 3,209 | 3,198 |
| Product dose omission issue | 2,543 | 27 |
| Off label use | 2,514 | 307 |
| Fatigue | 2,307 | 66 |
| Diarrhoea | 2,217 | 73 |
| Hospitalisation | 2,006 | 42 |
| Product use in unapproved indication | 1,783 | 102 |
| Somnolence | 1,768 | 12 |
| Nausea | 1,745 | 98 |