Cytochrome P450 2B6 Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Seizure | 6,632 | 5 | 109 | 2,014 | 45 |
| Death | 3,209 | 5 | 3,198 | 208 | 13 |
| Product dose omission issue | 2,543 | 6 | 27 | 438 | 9 |
| Off label use | 2,514 | 6 | 307 | 966 | 34 |
| Fatigue | 2,307 | 6 | 66 | 332 | 18 |
| Diarrhoea | 2,217 | 6 | 73 | 371 | 10 |
| Hospitalisation | 2,006 | 4 | 42 | 1,994 | 5 |
| Product use in unapproved indication | 1,783 | 4 | 102 | 273 | 9 |
| Somnolence | 1,768 | 6 | 12 | 284 | 8 |
| Nausea | 1,745 | 6 | 98 | 415 | 28 |
| Vomiting | 1,450 | 6 | 107 | 464 | 28 |
| Drug ineffective | 1,269 | 6 | 67 | 225 | 28 |
| Neoplasm progression | 1,172 | 2 | 350 | 225 | 12 |
| Decreased appetite | 1,050 | 6 | 54 | 263 | 16 |
| Dizziness | 1,046 | 6 | 27 | 228 | 11 |
| Weight decreased | 929 | 6 | 32 | 248 | 3 |
| Headache | 886 | 6 | 33 | 151 | 14 |
| Weight increased | 836 | 5 | 8 | 101 | 4 |
| Fall | 763 | 5 | 23 | 298 | 10 |
| Pneumonia | 741 | 5 | 139 | 542 | 29 |
| Disease progression | 731 | 3 | 295 | 161 | 28 |
| Constipation | 718 | 6 | 46 | 182 | 22 |
| Rash | 705 | 6 | 14 | 99 | 12 |
| Product use issue | 692 | 5 | 54 | 108 | 5 |
| Insomnia | 635 | 6 | 6 | 91 | 4 |
| Condition aggravated | 627 | 4 | 22 | 118 | 6 |
| Asthenia | 599 | 6 | 72 | 220 | 13 |
| Pyrexia | 571 | 6 | 54 | 279 | 14 |
| Malaise | 561 | 7 | 52 | 167 | 5 |
| Dyspnoea | 559 | 6 | 120 | 255 | 18 |