Insomnia: Which Medications Cause It? (186,726 Reports Across 2,048 Drugs)
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Insomnia has been reported as an adverse event with 2,048 different drugs in the FDA's FAERS database, with 186,726 total reports. 5,393 of these reports resulted in death.The drugs most commonly associated with Insomnia are ADALIMUMAB, DULOXETINE, and ETANERCEPT.
186,726
Total Reports
2,048
Drugs Involved
5,393
Deaths
32,090
Hospitalizations
54.5 yrs
Average Patient Age
65.4% / 34.6%
Female / Male
Which Drugs Cause Insomnia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 6,888 | 1.4% | 1,336 | 2,880 | 1,323 |
| DULOXETINE | 5,270 | 10.1% | 37 | 506 | 77 |
| ETANERCEPT | 4,983 | 1.4% | 1,055 | 1,491 | 949 |
| PREGABALIN | 4,882 | 4.8% | 749 | 1,263 | 595 |
| METHOTREXATE | 4,757 | 1.9% | 1,144 | 2,073 | 1,355 |
| LEVOTHYROXINE | 4,663 | 7.6% | 31 | 504 | 155 |
| TOCILIZUMAB | 4,001 | 4.1% | 1,294 | 1,812 | 1,167 |
| PREDNISONE | 3,804 | 2.4% | 1,082 | 2,133 | 1,230 |
| LENALIDOMIDE | 3,651 | 1.0% | 75 | 416 | 47 |
| RITUXIMAB | 3,637 | 2.0% | 1,269 | 2,082 | 1,331 |
| OXYCODONE | 3,634 | 1.9% | 982 | 1,420 | 1,022 |
| LEFLUNOMIDE | 3,537 | 6.3% | 1,106 | 1,743 | 1,302 |
| ABATACEPT | 3,522 | 3.0% | 925 | 1,638 | 1,174 |
| TOFACITINIB | 3,415 | 2.2% | 873 | 1,411 | 1,003 |
| DUPILUMAB | 3,280 | 0.9% | 6 | 128 | 1 |
| ACETAMINOPHEN | 3,269 | 2.4% | 1,244 | 1,447 | 1,126 |
| APREMILAST | 3,023 | 2.2% | 837 | 1,030 | 800 |
| SODIUM OXYBATE | 2,993 | 4.9% | 6 | 214 | 2 |
| CERTOLIZUMAB PEGOL | 2,929 | 3.0% | 983 | 1,393 | 1,116 |
| NIRAPARIB | 2,861 | 13.2% | 57 | 571 | 97 |