Cytochrome P450 2C19 Inducers [MoA]: Side Effects & Safety Data for 10 Drugs
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Cytochrome P450 2C19 Inducers [MoA] includes 10 drugs with a combined 126,799 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
10
Drugs in Class
126,799
Combined Reports
All Cytochrome P450 2C19 Inducers [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| ENZALUTAMIDE | Xtandi | 49,270 | 9,676 | 9,282 | 19.6% |
| CARBAMAZEPINE | Carbamazepine | 24,577 | 2,156 | 9,608 | 8.8% |
| DABRAFENIB | Tafinlar | 19,305 | 4,165 | 5,325 | 21.6% |
| PHENYTOIN | PHENYTOIN SODIUM | 14,469 | 1,449 | 5,241 | 10.0% |
| RITONAVIR | Norvir | 11,980 | 1,190 | 2,925 | 9.9% |
| SPARSENTAN | FILSPARI | 3,280 | 18 | 209 | 0.5% |
| LETERMOVIR | PREVYMIS | 1,416 | 252 | 398 | 17.8% |
| FOSPHENYTOIN | CEREBYX | 1,378 | 166 | 646 | 12.0% |
| MITAPIVAT | PYRUKYND | 627 | 4 | 58 | 0.6% |
| NIROGACESTAT | OGSIVEO | 497 | 7 | 54 | 1.4% |
Common Side Effects in Cytochrome P450 2C19 Inducers [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Fatigue | 12,115 | 783 |
| Death | 10,522 | 10,504 |
| Drug ineffective | 10,208 | 733 |
| Malignant neoplasm progression | 6,400 | 2,190 |
| Nausea | 6,070 | 477 |
| Pyrexia | 5,825 | 522 |
| Asthenia | 5,212 | 546 |
| Dizziness | 5,155 | 258 |
| Seizure | 4,992 | 258 |
| Diarrhoea | 4,550 | 378 |