Histamine-1 Receptor Antagonist [EPC]: Side Effects & Safety Data for 13 Drugs
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Histamine-1 Receptor Antagonist [EPC] includes 13 drugs with a combined 128,132 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
13
Drugs in Class
128,132
Combined Reports
All Histamine-1 Receptor Antagonist [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| CETIRIZINE | Cetirizine | 47,655 | 4,787 | 8,423 | 10.0% |
| DIPHENHYDRAMINE | Allergy Relief | 25,827 | 10,508 | 6,849 | 40.7% |
| FEXOFENADINE | Fexofenadine HCl | 21,453 | 80 | 535 | 0.4% |
| LEVOCETIRIZINE | allergy relief | 10,782 | 554 | 884 | 5.1% |
| OLOPATADINE | PATADAY ONCE DAILY RELIEF | 8,787 | 89 | 171 | 1.0% |
| AZELASTINE | Azelastine Hydrochloride | 5,896 | 12 | 89 | 0.2% |
| DESLORATADINE | Desloratadine | 3,141 | 160 | 1,389 | 5.1% |
| DIMENHYDRINATE | Driminate | 1,934 | 160 | 836 | 8.3% |
| CHLORPHENIRAMINE | ACTIDOM DA | 1,919 | 607 | 663 | 31.6% |
| ALCAFTADINE | Alcaftadine | 465 | 0 | 4 | N/A |
| BEPOTASTINE BESILATE | Bepotastine Besilate Ophthalmic Solution 1.5% | 142 | 5 | 12 | 3.5% |
| BEPOTASTINE | Bepreve | 87 | 6 | 34 | 6.9% |
| CARBINOXAMINE | Carbinoxamine Maleate Extended-Release Oral Suspension | 44 | 3 | 2 | 6.8% |
Common Side Effects in Histamine-1 Receptor Antagonist [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 30,268 | 1,808 |
| Fatigue | 14,283 | 2,706 |
| Pain | 12,211 | 2,224 |
| Off label use | 11,845 | 2,385 |
| Treatment failure | 10,936 | 1,443 |
| Rheumatoid arthritis | 9,708 | 2,437 |
| Abdominal discomfort | 9,662 | 2,183 |
| Alopecia | 9,261 | 2,117 |
| Rash | 9,062 | 2,389 |
| Systemic lupus erythematosus | 8,794 | 2,324 |