Opioid Antagonist [EPC]: Side Effects & Safety Data for 7 Drugs
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Opioid Antagonist [EPC] includes 7 drugs with a combined 32,468 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
7
Drugs in Class
32,468
Combined Reports
All Opioid Antagonist [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| NALTREXONE | NALTREXONE HYDROCHLORIDE | 25,624 | 1,106 | 2,843 | 4.3% |
| NALOXONE | Naloxone Hydrochloride | 2,859 | 779 | 1,033 | 27.2% |
| NALOXEGOL OXALATE | MOVANTIK | 2,212 | 154 | 335 | 7.0% |
| METHYLNALTREXONE | Relistor | 826 | 242 | 108 | 29.3% |
| NALDEMEDINE | SYMPROIC | 677 | 167 | 105 | 24.7% |
| NALMEFENE | Zurnai | 197 | 77 | 118 | 39.1% |
| ALVIMOPAN | Alvimopan | 73 | 4 | 20 | 5.5% |
Common Side Effects in Opioid Antagonist [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Injection site reaction | 4,360 | 5 |
| Injection site pain | 3,001 | 4 |
| Drug ineffective | 2,283 | 195 |
| Nausea | 2,138 | 20 |
| Alcoholism | 1,928 | 17 |
| Injection site mass | 1,849 | 1 |
| Pain | 1,707 | 21 |
| Fatigue | 1,583 | 8 |
| Drug dependence | 1,523 | 96 |
| Off label use | 1,418 | 62 |