Drug dependence: Which Medications Cause It? (148,555 Reports Across 782 Drugs)
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Drug dependence has been reported as an adverse event with 782 different drugs in the FDA's FAERS database, with 148,555 total reports. 15,278 of these reports resulted in death.The drugs most commonly associated with Drug dependence are OXYCODONE, ACETAMINOPHEN\HYDROCODONE, and MORPHINE.
148,555
Total Reports
782
Drugs Involved
15,278
Deaths
10,645
Hospitalizations
44.0 yrs
Average Patient Age
41.0% / 59.0%
Female / Male
Which Drugs Cause Drug dependence Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 104,927 | 55.1% | 12,600 | 4,694 | 284 |
| ACETAMINOPHEN\HYDROCODONE | 41,789 | 38.4% | 5,014 | 2,812 | 119 |
| MORPHINE | 40,036 | 33.2% | 4,308 | 2,502 | 198 |
| HYDROMORPHONE | 39,714 | 47.6% | 4,428 | 2,454 | 124 |
| ACETAMINOPHEN\OXYCODONE | 34,821 | 35.0% | 4,882 | 2,609 | 113 |
| TRAMADOL | 21,018 | 27.8% | 2,234 | 1,918 | 142 |
| BUPRENORPHINE | 16,730 | 20.4% | 1,996 | 1,362 | 77 |
| HYDROCODONE | 14,400 | 30.1% | 1,840 | 710 | 33 |
| ACETAMINOPHEN\OXYCODONE\OXYCODONE TEREPHTHALATE | 10,040 | 85.7% | 832 | 596 | 35 |
| FENTANYL | 7,970 | 8.4% | 1,928 | 1,147 | 82 |
| METHADONE | 5,739 | 21.8% | 660 | 656 | 57 |
| BUPRENORPHINE\NALOXONE | 4,755 | 22.0% | 253 | 483 | 50 |
| OXYMORPHONE | 3,790 | 10.0% | 978 | 575 | 7 |
| DIAMORPHINE | 3,325 | 37.0% | 875 | 549 | 33 |
| ALPRAZOLAM | 2,743 | 5.7% | 563 | 837 | 82 |
| PREGABALIN | 2,348 | 2.3% | 225 | 584 | 82 |
| OMEPRAZOLE | 1,854 | 2.1% | 22 | 62 | 2 |
| ASPIRIN\OXYCODONE | 1,773 | 6.9% | 729 | 311 | 1 |
| DIAZEPAM | 1,731 | 4.5% | 419 | 664 | 119 |
| OXYMETAZOLINE | 1,567 | 34.4% | 8 | 7 | 1 |