Opioid Antagonist [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Injection site reaction | 4,360 | 1 | 5 | 213 | 6 |
| Injection site pain | 3,001 | 2 | 4 | 155 | 9 |
| Drug ineffective | 2,283 | 6 | 195 | 575 | 169 |
| Nausea | 2,138 | 6 | 20 | 219 | 19 |
| Alcoholism | 1,928 | 1 | 17 | 255 | 7 |
| Injection site mass | 1,849 | 1 | 1 | 88 | 7 |
| Pain | 1,707 | 5 | 21 | 229 | 6 |
| Fatigue | 1,583 | 4 | 8 | 177 | 2 |
| Drug dependence | 1,523 | 2 | 96 | 207 | 17 |
| Off label use | 1,418 | 6 | 62 | 192 | 47 |
| Feeling abnormal | 1,389 | 5 | 3 | 73 | 6 |
| Headache | 1,385 | 5 | 4 | 112 | 12 |
| Malaise | 1,275 | 6 | 13 | 159 | 3 |
| Diarrhoea | 1,172 | 6 | 33 | 187 | 11 |
| Vomiting | 1,165 | 5 | 26 | 244 | 13 |
| Insomnia | 1,112 | 4 | 3 | 121 | 6 |
| Anxiety | 1,048 | 4 | 7 | 113 | 7 |
| Overdose | 983 | 3 | 464 | 288 | 97 |
| Dizziness | 952 | 6 | 5 | 100 | 5 |
| Death | 952 | 5 | 942 | 41 | 15 |
| Injection site induration | 866 | 1 | 0 | 59 | 6 |
| Depression | 825 | 4 | 10 | 98 | 9 |
| Decreased appetite | 822 | 5 | 5 | 81 | 11 |
| Toxicity to various agents | 816 | 3 | 605 | 309 | 85 |
| Drug withdrawal syndrome | 771 | 6 | 14 | 205 | 25 |
| Tremor | 732 | 6 | 10 | 97 | 14 |
| Withdrawal syndrome | 730 | 5 | 19 | 138 | 14 |
| Therapeutic response shortened | 658 | 1 | 3 | 20 | 2 |
| Abdominal pain upper | 648 | 5 | 1 | 70 | 3 |
| Injection site swelling | 638 | 1 | 0 | 56 | 2 |