Overdose: Which Medications Cause It? (170,371 Reports Across 1,715 Drugs)
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Overdose has been reported as an adverse event with 1,715 different drugs in the FDA's FAERS database, with 170,371 total reports. 32,489 of these reports resulted in death.The drugs most commonly associated with Overdose are OXYCODONE, ACETAMINOPHEN\HYDROCODONE, and ACETAMINOPHEN\OXYCODONE.
170,371
Total Reports
1,715
Drugs Involved
32,489
Deaths
40,049
Hospitalizations
43.5 yrs
Average Patient Age
50.4% / 49.6%
Female / Male
Which Drugs Cause Overdose Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 51,222 | 26.9% | 17,035 | 3,302 | 613 |
| ACETAMINOPHEN\HYDROCODONE | 30,936 | 28.4% | 9,570 | 1,709 | 136 |
| ACETAMINOPHEN\OXYCODONE | 29,876 | 30.0% | 11,176 | 1,614 | 155 |
| MORPHINE | 26,942 | 22.3% | 9,637 | 2,041 | 428 |
| HYDROMORPHONE | 25,322 | 30.4% | 9,229 | 1,528 | 178 |
| BUPRENORPHINE | 13,977 | 17.0% | 6,924 | 1,047 | 265 |
| ADAPALENE | 13,263 | 7.3% | 2 | 3 | 0 |
| FENTANYL | 12,762 | 13.5% | 8,277 | 1,331 | 364 |
| TRAMADOL | 12,705 | 16.8% | 2,989 | 1,915 | 458 |
| HYDROCODONE | 11,585 | 24.2% | 7,001 | 527 | 59 |
| OXYMORPHONE | 9,852 | 25.9% | 6,994 | 259 | 22 |
| AVOBENZONE\OCTISALATE\OCTOCRYLENE | 9,745 | 7.5% | 0 | 2 | 0 |
| ACETAMINOPHEN | 7,917 | 5.8% | 1,751 | 5,033 | 1,124 |
| ASPIRIN\OXYCODONE | 6,882 | 26.7% | 6,199 | 174 | 9 |
| TAPENTADOL | 5,843 | 20.0% | 5,582 | 221 | 12 |
| ACETAMINOPHEN\OXYCODONE\OXYCODONE TEREPHTHALATE | 4,000 | 34.2% | 647 | 330 | 29 |
| METHADONE | 3,472 | 13.2% | 1,240 | 553 | 155 |
| QUETIAPINE | 3,279 | 4.5% | 800 | 1,910 | 767 |
| ALPRAZOLAM | 2,967 | 6.1% | 1,205 | 1,167 | 271 |
| AMLODIPINE | 2,609 | 4.0% | 432 | 2,121 | 982 |
Top 3 Drugs Associated With Overdose
51,222 reports
30,936 reports
29,876 reports