Serotonin Uptake Inhibitors [MoA]: Side Effects & Safety Data for 12 Drugs
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Serotonin Uptake Inhibitors [MoA] includes 12 drugs with a combined 288,467 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
12
Drugs in Class
288,467
Combined Reports
All Serotonin Uptake Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| SERTRALINE | Sertraline Hydrochloride | 59,788 | 6,889 | 19,327 | 11.5% |
| DULOXETINE | Duloxetine Hydrochloride | 52,188 | 4,044 | 10,622 | 7.7% |
| VENLAFAXINE | Venlafaxine Hydrochloride | 47,931 | 7,521 | 15,749 | 15.7% |
| FLUOXETINE | Fluoxetine | 31,181 | 5,534 | 11,247 | 17.7% |
| ESCITALOPRAM OXALATE | Escitalopram | 30,355 | 3,531 | 11,942 | 11.6% |
| CITALOPRAM HYDROBROMIDE | Citalopram Hydrobromide | 27,049 | 6,745 | 9,074 | 24.9% |
| PAROXETINE | Paroxetine | 21,439 | 2,854 | 8,171 | 13.3% |
| DESVENLAFAXINE | Desvenlafaxine Succinate | 8,922 | 447 | 1,093 | 5.0% |
| CITALOPRAM | Citalopram | 4,166 | 1,947 | 1,002 | 46.7% |
| FLUVOXAMINE | Fluvoxamine Maleate | 2,678 | 344 | 1,092 | 12.8% |
| MILNACIPRAN | Savella | 1,392 | 120 | 274 | 8.6% |
| LEVOMILNACIPRAN | Fetzima | 1,378 | 382 | 378 | 27.7% |
Common Side Effects in Serotonin Uptake Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 25,702 | 773 |
| Nausea | 19,661 | 1,043 |
| Toxicity to various agents | 19,421 | 11,843 |
| Dizziness | 17,673 | 1,227 |
| Headache | 16,551 | 1,229 |
| Anxiety | 16,532 | 476 |
| Fatigue | 15,451 | 1,204 |
| Completed suicide | 14,996 | 14,931 |
| Insomnia | 13,989 | 1,082 |
| Off label use | 13,737 | 1,072 |