Tricyclic Antidepressant [EPC]: Side Effects & Safety Data for 9 Drugs
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Tricyclic Antidepressant [EPC] includes 9 drugs with a combined 36,683 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
9
Drugs in Class
36,683
Combined Reports
All Tricyclic Antidepressant [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| AMITRIPTYLINE | AMITRIPTYLINE HYDROCHLORIDE | 20,382 | 4,837 | 7,290 | 23.7% |
| NORTRIPTYLINE | Nortriptyline Hydrochloride | 6,073 | 1,810 | 1,398 | 29.8% |
| DOXEPIN | doxepin hydrochloride | 4,021 | 1,613 | 1,091 | 40.1% |
| CLOMIPRAMINE | Clomipramine Hydrochloride | 3,811 | 497 | 1,967 | 13.0% |
| IMIPRAMINE | Imipramine Hydrochloride | 1,077 | 242 | 338 | 22.5% |
| TRIMIPRAMINE | Trimipramine Maleate | 683 | 114 | 354 | 16.7% |
| DESIPRAMINE | Norpramin | 426 | 136 | 91 | 31.9% |
| AMOXAPINE | Amoxapine | 159 | 62 | 61 | 39.0% |
| PROTRIPTYLINE | Protriptyline Hydrochloride | 51 | 1 | 9 | 2.0% |
Common Side Effects in Tricyclic Antidepressant [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Toxicity to various agents | 5,477 | 3,492 |
| Drug ineffective | 4,631 | 215 |
| Completed suicide | 3,493 | 3,482 |
| Off label use | 3,132 | 283 |
| Pain | 2,198 | 219 |
| Overdose | 2,065 | 804 |
| Fatigue | 1,894 | 182 |
| Drug abuse | 1,874 | 1,235 |
| Nausea | 1,845 | 66 |
| Hyperhidrosis | 1,820 | 150 |