Does ACETAMINOPHEN\CODEINE Cause Duodenal ulcer perforation? 762 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 762 reports of Duodenal ulcer perforation have been filed in association with ACETAMINOPHEN\CODEINE. This represents 5.0% of all adverse event reports for ACETAMINOPHEN\CODEINE.
762
Reports of Duodenal ulcer perforation with ACETAMINOPHEN\CODEINE
5.0%
of all ACETAMINOPHEN\CODEINE reports
709
Deaths
661
Hospitalizations
How Dangerous Is Duodenal ulcer perforation From ACETAMINOPHEN\CODEINE?
Of the 762 reports, 709 (93.0%) resulted in death, 661 (86.7%) required hospitalization, and 668 (87.7%) were considered life-threatening.
Is Duodenal ulcer perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN\CODEINE. However, 762 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN\CODEINE Cause?
Dependence (3,857)
Overdose (2,600)
Pain (1,712)
Off label use (1,309)
Drug ineffective (1,300)
Nausea (1,291)
Drug dependence (1,273)
Fatigue (1,240)
Vomiting (1,224)
Depression (1,153)
What Other Drugs Cause Duodenal ulcer perforation?
METHOTREXATE (4,239)
LEFLUNOMIDE (4,200)
FOLIC ACID (4,152)
ABATACEPT (4,147)
TOCILIZUMAB (4,130)
DICLOFENAC (4,120)
CETIRIZINE (4,117)
DESOXIMETASONE (4,084)
RITUXIMAB (4,081)
PREDNISONE (4,060)
Which ACETAMINOPHEN\CODEINE Alternatives Have Lower Duodenal ulcer perforation Risk?
ACETAMINOPHEN\CODEINE vs ACETAMINOPHEN\DEXTROMETHORPHAN HYDROBROMIDE
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