Does AFATINIB Cause Agranulocytosis? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Agranulocytosis have been filed in association with AFATINIB (Gilotrif). This represents 0.1% of all adverse event reports for AFATINIB.
7
Reports of Agranulocytosis with AFATINIB
0.1%
of all AFATINIB reports
0
Deaths
7
Hospitalizations
How Dangerous Is Agranulocytosis From AFATINIB?
Of the 7 reports, 7 (100.0%) required hospitalization, and 6 (85.7%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which AFATINIB Alternatives Have Lower Agranulocytosis Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE